Director- Quantitative Systems Pharmacology Scientist, PK/PD & Pharmacometrics

Location: Indianapolis
Posted on: June 23, 2025

Job Description:

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Eli Lilly and Company is committed to using its innovation-based strategy to discover, develop and deliver innovative medicines that help improve the lives of people. In support of this goal, the PKPD & Pharmacometrics (PMx) organization provides leadership and technical expertise to support the discovery and development of new medicines from preclinical lead molecule identification to clinical post-drug approval, with the goal of identifying and developing the right drug with the right dose for the right patient using model-informed drug research and development (MIDD) approaches. To further advance the science in this subject area, we are seeking a scientific director who will lead a group of quantitative systems pharmacology (QSP) computational scientists in supporting the portfolio. We are passionate about making an impact in the lives of our patients, developing people to their full potential, and pushing the boundaries of science. Consider joining Team Lilly in Indianapolis to contribute to Lilly’s drug discovery and development efforts. Key Responsibilities: Supervise a group of QSP scientists, with associated responsibilities including performance, resource allocation and staff development. Provide scientific leadership to project teams to support the selection of the right target, molecule, dose, patient population, and development strategies. Develop and implement modeling strategies, contribute to project team discussions, and guide decisions with quantitative approaches into drug discovery and/or development Collaboratively develop platform models and modeling workflows that extend across multiple projects and phases of discovery & development. Communicate quantitative data, both internally and in the scientific community Basic Qualifications: PhD in Engineering, Biology, Computational Sciences, Mathematics, Pharmacokinetics/Pharmacodynamics, or a related field with 5 years of relevant work experience with quantitative systems pharmacology modeling (QSP) in industry or academia. Master’s degree with 10 years of industry experience and demonstrated impact (e.g., publications) Previous people management experience is required, though this may include management in a matrix environment. Additional Skills/Preferences: Knowledge and expertise advancing and implementing QSP model-informed approaches in drug discovery and development. Strong interpersonal communication skills, including demonstrated experience working in a team environment. Direct experience with mathematical modeling workflows using relevant software such as R, Matlab, Python, etc. Adept at working with cross-functional colleagues Excellent self-management and organizational skills Familiarity or experience in immunology, cardiometabolic health, neuroscience or other therapeutic areas Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $168,000 - $294,800 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. WeAreLilly

Keywords: , Bloomington , Director- Quantitative Systems Pharmacology Scientist, PK/PD & Pharmacometrics, Science, Research & Development , Indianapolis, Indiana